null mutation वाक्य
उदाहरण वाक्य
मोबाइल
- Cripto s functions have been hypothesized from these null mutation studies.
- Functional null mutations in this gene cause Carney complex ( CNC ), an autosomal dominant multiple neoplasia syndrome.
- SOD2 knockout or null mutations cause growth inhibition on respiratory carbon sources in addition to decreased post-diauxic lifespan.
- The susceptible MHC class II RT1u haplotype on chromosome 20 and a null mutation in the GIMAP5 gene on chromosome 4.
- A third kind of nemaline myopathy in the Skeletal Muscle ?-Actin Gene ACTA1 is due to a recessive null mutation.
- A null mutation in motif D of the reverse transcriptase domain of the telomerase protein, hTERT, leads to this phenotype.
- Research has not yet revealed a cost of carrying the CCR5 null mutation that is as dramatic as the benefit conferred in the context of HIV-1 exposure.
- Mice with null mutations ( " knockouts " ) in Brn3a die at birth, due to developmental defects in the nucleus ambiguus, which is essential for respiration.
- In this research null mutations in the rhodopsin kinase and arrestin genes, each of which plays a role in terminating rhodopsin activity, caused light-dependent retinal degeneration.
- Knockout or null mutations in SOD1 are highly detrimental to aerobic growth in the yeast " Saccharomyces cerevisiae " and result in a dramatic reduction in post-diauxic lifespan.
- Although the homozygous Brn3a null mutation is lethal at birth in mice, Brn3a null heterozygotes have no known phenotype . i . e . the Brn3a null mutation is completely recessive.
- Although the homozygous Brn3a null mutation is lethal at birth in mice, Brn3a null heterozygotes have no known phenotype . i . e . the Brn3a null mutation is completely recessive.
- Transgenic mice homozygous for a null mutation of the " JUP " gene die around embryonic day 12 from substantial defects in adherens junctions and a lack of functional desmosomes in the heart.
- "Clock " mutant organisms can either possess a null mutation or an antimorphic allele at the " Clock " locus that codes for an antagonist to the wild-type protein.
- In " Mitotic cell growth and spore germination are not compromised when these genes are deleted, but diploids that are homozygous for a SAT-1 null mutation exhibit a decrease in sporulation efficiency.
- GAP43 has been termed a'growth'or'plasticity'protein because it is expressed at high levels in presynaptic terminal, its null mutation leading to death within days after birth due to axon pathfinding defects.
- But null mutation of coronin in " D . discoideum " resulted in impaired cytokinesis, and many actin mediated processes like endocytosis, cell motility etc . Later on, the protein was identified in many eukaryotic cells.
- From studies with ztl-1 mutants, which have a single missense mutation in the kelch domain of the protein and effectively cause a ztl null mutation, TOC1 protein has been found to be stabilized and TOC1 cycling largely eliminated.
- In 10 20 % of endometrial cancers, mostly Grade 3 ( the highest PTEN . In 20 % of endometrial hyperplasias and 50 % of endometrioid cancers, PTEN suffers a loss-of-function mutation or a null mutation, making it less effective or completely ineffective.
- Zinc finger protein 318 ( ZFP318 ) has a role in the promotion of IgD expression and controlling the alternative splicing of the long pre-mRNA . In immature B cells that mainly express the ? transcript, there is no ZFP318 expression, but in mature B cells with dual IgM and IgD expression, both ? and ? transcript is made and ZFP318 is expressed . found in mice that null mutations in ZFP318 resulted in no IgD expression.
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